Gene

deptor

ID

ZDB-GENE-061013-453

Name

DEP domain containing MTOR-interacting protein

Symbol

deptor Nomenclature History

Previous Names

depdc6
fd14h03
fi11e09
wu:fd14h03
wu:fi11e09
zgc:152943

Type

protein_coding_gene

Location

Chr: 16 Mapping Details/Browsers

Description

Predicted to be involved in intracellular signal transduction; negative regulation of TOR signaling; and negative regulation of protein kinase activity. Orthologous to human DEPTOR (DEP domain containing MTOR interacting protein).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With deptor Human Ortholog

No data available

Associated With deptor Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000591	DEP domain
Domain	IPR001478	PDZ domain
Domain	IPR037335	DEP domain-containing mTOR-interacting protein, DEP domain 1
Domain	IPR037336	DEP domain-containing mTOR-interacting protein, DEP domain 2
Family	IPR051832	Regulators of mTOR signaling and Rac activation
Homologous_superfamily	IPR036034	PDZ superfamily
Homologous_superfamily	IPR036388	Winged helix-like DNA-binding domain superfamily
Homologous_superfamily	IPR036390	Winged helix DNA-binding domain superfamily

Domain Details Per Protein

Protein	Length	DEP domain	DEP domain-containing mTOR-interacting protein, DEP domain 1	DEP domain-containing mTOR-interacting protein, DEP domain 2	PDZ domain	PDZ superfamily	Regulators of mTOR signaling and Rac activation	Winged helix DNA-binding domain superfamily	Winged helix-like DNA-binding domain superfamily
UniProtKB:A0A8M2BKU4 InterPro	407
UniProtKB:Q08BQ7 InterPro	348
UniProtKB:A0A8M1NBQ2 InterPro	365

Transcripts

Genome Browsers

Type	Name	Annotation Method	Length (nt)	Analysis
mRNA	deptor-201 (1) Ensembl	Ensembl	2,648 nt	Select Tool ZFIN BLAST
mRNA	deptor-202 (1) Ensembl	Ensembl	679 nt	Select Tool ZFIN BLAST
mRNA	deptor-203 (1) Ensembl	Ensembl	2,019 nt	Select Tool ZFIN BLAST
mRNA	deptor-204 (1) Ensembl	Ensembl	2,648 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations